Treatment and prognosisĪgain, both treatment and prognosis are significantly influenced by tumor type, morphology and location. Pons carries signals from cerebrum to medulla and cerebellum and contains the tracts that carry sensory signals to thalamus. May show anterior displacement of the basilar artery. Pons Pons contains the nuclei which relay signals associated with sleep, bladder control, equilibrium, taste, eye movement and facial expressions along with various other functions, from the forebrain to the cerebellum. Unless otherwise specified, the term brainstem glioma usually refers to the most common histology of a diffuse midline glioma H3 K27-altered although many other gliomas can be encountered in the brainstem (e.g. It handles unconscious processes and jobs, such as your sleep-wake cycle and breathing. Brainstem gliomas consist of a heterogeneous group that varies greatly in histology and prognosis. The pons is also called the pons Varolii ('bridge of Varolius'), after the Italian anatomist and surgeon Costanzo Varolio (154375).
The appearance will vary with the tumor type, thus please refer to individual articles. Your pons is a part of your brainstem, a structure that links your brain to your spinal cord. The pons (from Latin pons, 'bridge') is part of the brainstem that in humans and other bipeds lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum. Most common location for NF1 associated tumors Includes focal dorsally exophytic, focal, diffuse and cervicomedullary junction variantsĬervicomedullary junction tumors usually represent upper cervical tumors extending superiorly Tectal plate gliomas are typically indolent Includes diffuse, focal, exophytic and tectal variantsįocal brainstem gliomas are more common here than elsewhere in the brainstem Overall 5-year survival of pontine gliomas is 10% PathologyĪs a general rule, mesencephalic tumors tend to be of a lower grade than those in the pons and medulla 3.Ĭlassic location for the childhood "brainstem glioma" which tends to refer to a diffuse midline glioma, H3 K27–alteredįocal dorsally exophytic brainstem glioma is an uncommon variant accounting for only 10% of pontine tumors, and has a much better prognosis, as it usually represents a pilocytic astrocytoma Additionally, diffuse gliomas more frequently have multiple cranial nerve palsies. It is a group of nerves that function as a connection between the cerebrum and cerebellum ( pons is Latin for bridge ). The duration of symptoms is usually much shorter in diffuse gliomas (in contrast to focal gliomas), in which the history is typically very short (a few days) 4. The pons is the largest part of the brainstem, located above the medulla and below the midbrain. Although the exact presentation will vary according to the location and size of the tumor, in general patients will exhibit a combination of 4:
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